翻訳と辞書 Words near each other ・ Discovery and development of beta2 agonists ・ Discovery and development of cephalosporins ・ Discovery and development of cyclooxygenase 2 inhibitors ・ Discovery and development of direct thrombin inhibitors ・ Discovery and development of gliflozins ・ Discovery and development of HIV-protease inhibitors ・ Discovery and development of integrase inhibitors ・ Discovery and development of matrix metalloproteinase inhibitors ・ Discovery and development of memantine and related compounds ・ Discovery and development of neuraminidase inhibitors ・ Discovery and development of non-nucleoside reverse-transcriptase inhibitors ・ Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors ・ Discovery and development of phosphodiesterase 5 inhibitors ・ Discovery and development of proton pump inhibitors ・ Discovery and development of statins ・ Discovery and development of steroidal aromatase inhibitors ・ Discovery and development of triptans ・ Discovery and development of TRPV1 antagonists ・ Discovery and development of tubulin inhibitors ・ Discovery and exploration of the Solar System ・ Discovery and Launch ・ Discovery Arcade (Disneyland Paris) ・ Discovery Atlas ・ Discovery Aviation Model 201 ・ Discovery Bay ・ Discovery Bay (Antarctica) ・ Discovery Bay (Australia) ・ Discovery Bay (disambiguation) ・ Discovery Bay Coastal Park ・ Discovery Bay Ferry Pier Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Discovery and development of steroidal aromatase inhibitors ： ウィキペディア英語版 Discovery and development of steroidal aromatase inhibitors Aromatase inhibitors are a class of drugs that are mostly used for treating breast cancer in postmenopausal women. High levels of estrogen in breast tissue increases the risk of developing breast cancer and the enzyme Aromatase is good therapeutic target when treating breast cancer due to it being involved in the final step of estrogen biosynthetic pathway and also its inhibitation will not affect production of other steroids. Aromatase Inhibitors are classified into two categories based on their structure, Nonsteroidal and Steroidal which structure resembles the build of androstenedione.〔Ahmad, I., & Shagufta. (2015). Recent developments in steroidal and nonsteroidal aromatase inhibitors for the chemoprevention of estrogen-dependent breast cancer. European Journal of Medicinal Chemistry, 102, 375-386. doi:http://dx.doi.org/10.1016/j.ejmech.2015.08.010〕 Steroidal aromatase inhibitors irreversibly inhibit the enzyme by binding covalently to the binding site of aromatase so the substrate can't access it.〔 == History == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Discovery and development of steroidal aromatase inhibitors」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.